Successful reintroduction of methotrexate after pneumonitis in two patients with rheumatoid arthritis.
نویسندگان
چکیده
Two patients are described with severe and progressive rheumatoid arthritis in whom methotrexate was reintroduced despite previous methotrexate related pneumonitis. In both patients a marked improvement in disease control occurred without a recurrence of the pneumonitis.
منابع مشابه
هپاتوتوکسیسیتی متوتروکسات؛ خطری که نباید نادیده گرفته شود: معرفی 4 بیمار و مرور مطالب کاربردی
Introduction: Methotrexate is used increasingly for treatment of some diseases such as rheumatoid arthritis, psoriasis and Crohn. Bone marrow suppression, mucocutaneous lesions, pneumonitis, and hepatotoxicity are major side effects of this drug. Since methotrexate toxicity is dose dependent and is usually administered with low dose via a weekly regimen, its side effects are not commonly seen. ...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 51 2 شماره
صفحات -
تاریخ انتشار 1992